Blar i Brage NIH på forfatter "Frugé, Andrew D."
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Resistance training rejuvenates the mitochondrial methylome in aged human skeletal muscle
Ruple, Bradley A; Godwin, Joshua S.; Mesquita, Paulo H. C; Osburn, Shelby C; Vann, Christopher G; Lamb, Donald A; Sexton, Casey L; Candow, Darren G; Forbes, Scott C; Frugé, Andrew D.; Kavazis, Andreas N; Young, Kaelin C; Seaborne, Robert A.; Sharples, Adam; Roberts, Michael D (Peer reviewed; Journal article, 2021)Resistance training (RT) dynamically alters the skeletal muscle nuclear DNA methylome. However, no study has examined if RT affects the mitochondrial DNA (mtDNA) methylome. Herein, ten older, Caucasian untrained males (65 ... -
Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previously trained men
Sexton, Casey L.; McIntosh, Mason C.; Ruple, Bradley A.; Osburn, Shelby C.; Hollingsworth, Blake R.; Kontos, Nicholas J.; Agostinelli, Philip J.; Kavazis, Andreas N.; Ziegenfuss, Tim N.; Lopez, Hector L.; Young, Kaelin C.; Dwaraka, Varun B.; Mobley, Christopher B.; Sharples, Adam P.; Godwin, Joshua S.; Smith, Ryan; Frugé, Andrew D.; Roberts, Michael D. (Peer reviewed; Journal article, 2023)We sought to determine the skeletal muscle genome-wide DNA methylation and mRNA responses to one bout of lower load (LL) versus higher load (HL) resistance exercise. Trained college-aged males (n = 11, 23 ± 4 years old, 4 ...